Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 6/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23168311 | 1.00 | GPR52 (0.51) | GPR52FFAR1KCNH2MMP12TAAR1 | |
| SCHEMBL10009929 | 0.92 | HRH3 (0.43) | GPR52FFAR1KCNH2HDAC2 | |
| SCHEMBL27538475 | 0.89 | FFAR1 (0.47) | GPR52FFAR1KCNH2MMP12TAAR1 | |
| SCHEMBL448516 | 0.87 | GPR52 (0.55) | GPR52 | |
| SCHEMBL106847 | 0.87 | GPR52 (0.55) | GPR52 | |
| SCHEMBL21901329 | 0.84 | CYP1A2 (0.43) | GPR52FFAR1KCNH2TAAR1IDO1 | |
| SCHEMBL19326441 | 0.84 | CYP1A2 (0.43) | GPR52FFAR1KCNH2TAAR1IDO1 | |
| SCHEMBL10479589 | 0.83 | GPR52 (0.52) | GPR52 | |
| SCHEMBL10479586 | 0.83 | GPR52 (0.52) | GPR52 | |
| SCHEMBL20849604 | 0.83 | GPR52 (0.40) | GPR52FFAR1TAAR1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665885-A | FOR STABILIZING ORGANIC MATERIAL AGAINST THE DAMAGING INFLUENCE OF LIGHT, OXYGEN AND/OR HEAT | CIBA-GEIGY CORPORATION (US) | 1997-09-09 | — | — | US | disclosed |
| US-5637714-A | OXIDATION AND HEAT RESISTANCE; PHOTOSTABILITY | CIBA-GEIGY CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| US-5510402-A | STABILIZING POLYOLEFINS AND STYRENE COPOLYMERS AGAINST HEAT, OXIDATION AND ACTINIC RADIATION | CIBA-GEIGY CORPORATION (US) | 1996-04-23 | — | — | US | disclosed |
| US-5457204-A | For polymers | CIBA-GEIGY CORPORATION (US) | 1995-10-10 | — | — | US | disclosed |
| EP-0634399-A1 | Adducts of hindered amine-epoxides as stabilisers | CIBA-GEIGY AG (CH) | 1995-01-18 | — | — | EP | disclosed |