Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19198172 | 0.97 | SIGMAR1 (0.42) | GSRRNPEPSIGMAR1CPB2MAPT | |
| Ethylenediamine SCHEMBL19197826 | 0.95 | SIGMAR1 (0.43) | GSRRNPEPSIGMAR1CPB2ALDH1A1 | |
| SCHEMBL17102940 | 0.89 | SIGMAR1 (0.50) | SIGMAR1MAPTALDH1A1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL28600382 | 0.87 | SIGMAR1 (0.48) | SIGMAR1MAPTALDH1A1LMNACYP1A2 | |
| Water SCHEMBL28622482 | 0.87 | SIGMAR1 (0.48) | SIGMAR1MAPTALDH1A1LMNACYP1A2 | |
| SCHEMBL19197984 | 0.83 | SIGMAR1 (0.40) | SIGMAR1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL15710769 | 0.83 | SIGMAR1 (0.42) | SIGMAR1MAPTALDH1A1LMNACYP1A2 | |
| SCHEMBL19197827 | 0.82 | SIGMAR1 (0.39) | SIGMAR1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL15711008 | 0.81 | SIGMAR1 (0.41) | SIGMAR1MAPTALDH1A1LMNACYP1A2 | |
| SCHEMBL30131273 | 0.81 | SIGMAR1 (0.43) | SIGMAR1MAPTALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725477-B2 | Platinum compounds of malonic acid derivative having leaving group containing amino or alkylamino | BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD (CN) | 2017-08-08 | — | — | US | claimed |
| EP-2924044-B1 | PLATINUM COMPOUND OF MALONIC ACID DERIVATIVE HAVING LEAVING GROUP CONTAINING AMINO OR ALKYLAMINO | BEIJING SHUOBAI PHARMACEUTICAL CO LTD (CN) | 2018-10-31 | — | — | EP | disclosed |
| US-9725477-B2 | Platinum compounds of malonic acid derivative having leaving group containing amino or alkylamino | BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD (CN) | 2017-08-08 | — | — | US | disclosed |