Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.32 |
| ▸ | ARG2 | P78540 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19197827 | 0.92 | SIGMAR1 (0.39) | SIGMAR1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL19197988 | 0.89 | SIGMAR1 (0.41) | SIGMAR1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL19197994 | 0.89 | SIGMAR1 (0.37) | SIGMAR1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL17102940 | 0.86 | SIGMAR1 (0.50) | SIGMAR1CHRM2CHRM4CHRM1CHRM3 | |
| Ethylenediamine SCHEMBL19197826 | 0.85 | SIGMAR1 (0.43) | SIGMAR1CHRM2CHRM4CHRM1CHRM3 | |
| Water SCHEMBL28622482 | 0.84 | SIGMAR1 (0.48) | SIGMAR1CHRM2CHRM4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL28600382 | 0.84 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1LMNACYP1A2CYP2D6 | |
| Putrescine SCHEMBL19198229 | 0.83 | GSR (0.44) | SIGMAR1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL19198172 | 0.83 | SIGMAR1 (0.42) | SIGMAR1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL19198230 | 0.82 | CHRM2 (0.35) | SIGMAR1CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725477-B2 | Platinum compounds of malonic acid derivative having leaving group containing amino or alkylamino | BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD (CN) | 2017-08-08 | — | — | US | claimed |
| EP-2924044-B1 | PLATINUM COMPOUND OF MALONIC ACID DERIVATIVE HAVING LEAVING GROUP CONTAINING AMINO OR ALKYLAMINO | BEIJING SHUOBAI PHARMACEUTICAL CO LTD (CN) | 2018-10-31 | — | — | EP | disclosed |
| US-9725477-B2 | Platinum compounds of malonic acid derivative having leaving group containing amino or alkylamino | BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD (CN) | 2017-08-08 | — | — | US | disclosed |