Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.58 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.58 |
| ▸ | ALPL | P05186 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30520641 | 1.00 | PDE4B (0.58) | PDE4BKDM4CALPLKDM4EKMT2A | |
| SCHEMBL30520316 | 0.85 | CYP1A2 (0.61) | PDE4BKDM4CALPLKMT2ACYP1A2 | |
| SCHEMBL19198190 | 0.85 | CYP1A2 (0.61) | PDE4BKDM4CALPLKMT2ACYP1A2 | |
| SCHEMBL30520200 | 0.82 | CYP11B2 (0.53) | PDE4BKDM4EKMT2ASGMS2SLC6A2 | |
| SCHEMBL19197790 | 0.82 | CYP11B2 (0.53) | PDE4BKDM4EKMT2ASGMS2SLC6A2 | |
| SCHEMBL19197930 | 0.82 | MEN1 (0.53) | PDE4BKDM4EKMT2ALMNARAB9A | |
| SCHEMBL30520433 | 0.82 | MEN1 (0.53) | PDE4BKDM4EKMT2ALMNARAB9A | |
| SCHEMBL30520275 | 0.80 | KDM4E (0.56) | PDE4BALPLKDM4EKMT2ALMNA | |
| SCHEMBL19197929 | 0.80 | KDM4E (0.56) | PDE4BALPLKDM4EKMT2ALMNA | |
| SCHEMBL4847902 | 0.77 | PKM (0.51) | KDM4CALPLKDM4EKMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286917-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2023-09-14 | — | — | US | disclosed |
| US-9725441-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286917-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM5A, KDM1A | PDE4B 346/4885KDM4C 18/4885ALPL 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.