Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920428 | 0.84 | L3MBTL1 (0.51) | L3MBTL1MAPTNPSR1KDM4EMEN1 | |
| SCHEMBL11066410 | 0.84 | KDM4E (0.60) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL15800965 | 0.80 | L3MBTL1 (0.61) | L3MBTL1MAPTNPSR1KDM4EMEN1 | |
| SCHEMBL9001338 | 0.79 | MEN1 (0.54) | L3MBTL1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL7520478 | 0.79 | KDM4E (0.54) | L3MBTL1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL156467 | 0.78 | KDM4E (0.58) | L3MBTL1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL10783529 | 0.77 | L3MBTL1 (0.84) | L3MBTL1MAPTNPSR1KDM4EMEN1 | |
| SCHEMBL1244995 | 0.77 | KDM4E (0.58) | KDM4EKMT2AHPGDATM | |
| SCHEMBL10591123 | 0.77 | PPARG (0.53) | L3MBTL1MAPTNPSR1KDM4EMEN1 | |
| SCHEMBL11068263 | 0.77 | KDM4E (0.59) | L3MBTL1MAPTKDM4EKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225325-B1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON INC (CH) | 2011-06-01 | — | — | EP | claimed |