Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668197 | 0.79 | NQO1 (0.42) | ALDH1A1HSD17B10FABP3FABP4FABP5 | |
| SCHEMBL3139616 | 0.77 | TTR (0.43) | TTRFABP3FABP4FABP5ACP1 | |
| SCHEMBL27966425 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ING2LMNANT5E | |
| SCHEMBL10533596 | 0.75 | SELL (0.48) | ALDH1A1HSD17B10FABP3FABP4FABP5 | |
| SCHEMBL19199331 | 0.75 | TTR (0.37) | TTRALDH1A1HSD17B10FABP3FABP4 | |
| SCHEMBL19199477 | 0.75 | HSD17B10 (0.39) | TTRALDH1A1HSD17B10ACP1ING2 | |
| SCHEMBL7095349 | 0.74 | ING2 (0.39) | TTRALDH1A1HSD17B10FABP3FABP4 | |
| SCHEMBL17810257 | 0.73 | RAPGEF4 (0.42) | TTRFABP3FABP4FABP5ACP1 | |
| SCHEMBL668351 | 0.70 | ING2 (0.37) | TTRALDH1A1HSD17B10FABP3FABP4 | |
| SCHEMBL28020177 | 0.70 | ING2 (0.37) | TTRALDH1A1HSD17B10FABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017132484-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | ACatechol, Inc. (US) | 2017-08-03 | — | — | WO | disclosed |