Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 8/20 | 0.48 |
| ▸ | CDC7 | O00311 | 3/20 | 0.48 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2691019 | 0.86 | ALDH1A1 (0.71) | ALDH1A1HPGDHSD17B10FNTAFNTB | |
| SCHEMBL1919770 | 0.86 | FNTA (0.55) | ALDH1A1HPGDHSD17B10FNTAFNTB | |
| SCHEMBL16075311 | 0.85 | ALDH1A1 (0.59) | ALDH1A1HPGDHSD17B10DHODHCDC7 | |
| SCHEMBL1919084 | 0.83 | ALDH1A1 (0.74) | ALDH1A1HPGDHSD17B10DHODHCDC7 | |
| SCHEMBL1919773 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10DHODHCDC7 | |
| SCHEMBL17396343 | 0.81 | FNTA (0.46) | ALDH1A1HPGDHSD17B10FNTAFNTB | |
| SCHEMBL1918353 | 0.81 | DHODH (0.62) | ALDH1A1HPGDHSD17B10DHODHCDC7 | |
| SCHEMBL1777440 | 0.81 | HRH2 (0.47) | ALDH1A1HPGDHSD17B10FNTAFNTB | |
| SCHEMBL1919885 | 0.79 | ALDH1A1 (0.61) | ALDH1A1HPGDHSD17B10DHODHCDC7 | |
| SCHEMBL5899899 | 0.79 | CDC7 (0.68) | ALDH1A1FNTAFNTBCDC7DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
| EP-2326640-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2011-06-01 | — | — | EP | disclosed |
| WO-2010013222-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | ALDH1A1 2042/4885HPGD 563/4885HSD17B10 1793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.