Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 2/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202112 | 0.78 | TRPA1 (0.38) | HSD17B10ALDH1A1HPGDHIF1ATP53 | |
| SCHEMBL2552952 | 0.77 | HSD17B10 (0.40) | HSD17B10ALDH1A1HPGDHIF1ATP53 | |
| SCHEMBL19199573 | 0.74 | HSD17B10 (0.35) | HSD17B10ALDH1A1HPGDHIF1ATP53 | |
| SCHEMBL31256 | 0.73 | COMT (0.43) | HSD17B10ALDH1A1HPGDHIF1ATP53 | |
| SCHEMBL29373188 | 0.73 | COMT (0.43) | HSD17B10ALDH1A1HPGDHIF1ATP53 | |
| SCHEMBL19202243 | 0.72 | IDO1 (0.52) | IDO1HSD17B10ALDH1A1HPGDALOX15 | |
| SCHEMBL11036814 | 0.72 | PRMT1 (0.48) | IDO1HSD17B10ALDH1A1HPGDHIF1A | |
| SCHEMBL3218328 | 0.71 | COMT (0.42) | HSD17B10ALDH1A1HPGDHIF1ATP53 | |
| SCHEMBL19730612 | 0.69 | ALDH1A1 (0.48) | IDO1HSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL19193494 | 0.69 | ALDH1A1 (0.41) | HSD17B10ALDH1A1HPGDHIF1AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017218499-A1 | IONIC POLYMERS AND THEIR USE AS WET-ADHESIVES AND COATINGS | ACatechol, Inc. (US) | 2017-12-21 | — | — | WO | disclosed |
| WO-2017132463-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | ACatechol, Inc. (US) | 2017-08-03 | — | — | WO | disclosed |