Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.68 |
| ▸ | EGFR | P00533 | 3/20 | 0.68 |
| ▸ | TEC | P42680 | 1/20 | 0.68 |
| ▸ | BMX | P51813 | 1/20 | 0.56 |
| ▸ | ITK | Q08881 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19203239 | 0.95 | BTK (0.64) | BTKEGFRTECBMXITK | |
| SCHEMBL19202397 | 0.95 | BTK (0.64) | BTKEGFRTECBMXITK | |
| SCHEMBL24083406 | 0.92 | BTK (0.59) | BTKEGFRTECBMXITK | |
| SCHEMBL19202583 | 0.90 | BTK (0.70) | BTKEGFRTECBMXITK | |
| SCHEMBL24083391 | 0.90 | BTK (0.56) | BTKEGFRTECBMXITK | |
| SCHEMBL24083394 | 0.84 | BTK (0.52) | BTKEGFRTECITK | |
| SCHEMBL24083387 | 0.83 | BTK (0.46) | BTKEGFRTEC | |
| SCHEMBL19202672 | 0.83 | BTK (0.50) | BTKEGFRTECBMXITK | |
| SCHEMBL24083370 | 0.83 | BTK (0.51) | BTKEGFRTECBMXITK | |
| SCHEMBL19203234 | 0.82 | BTK (0.60) | BTKEGFRTECBMX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017128917-A1 | PARAZOLE CONDENSED-RING DERIVATIVES AND PREPARATION METHOD THEREOF AND APPLICATION THEREOF IN TREATMENT OF CANCERS, INFLAMMATION AND IMMUNE DISEASES | 北京诺诚健华医药科技有限公司 | 2017-08-03 | — | — | WO | disclosed |