Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.51 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | TEC | P42680 | 1/20 | 0.47 |
| ▸ | BMX | P51813 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19203239 | 0.89 | BTK (0.64) | BTKEGFRTECBMXITK | |
| SCHEMBL19202397 | 0.89 | BTK (0.64) | BTKEGFRTECBMXITK | |
| SCHEMBL19202672 | 0.84 | BTK (0.50) | BTKEGFRTECBMXITK | |
| SCHEMBL19202583 | 0.84 | BTK (0.70) | BTKEGFRTECBMXITK | |
| SCHEMBL19202565 | 0.83 | BTK (0.68) | BTKEGFRTECBMXITK | |
| SCHEMBL24083366 | 0.82 | BTK (0.70) | BTKEGFRTECITK | |
| SCHEMBL19202369 | 0.77 | BTK (0.70) | BTKEGFRTECBMXITK | |
| SCHEMBL24083406 | 0.76 | BTK (0.59) | BTKEGFRTECBMXITK | |
| SCHEMBL19202379 | 0.74 | BTK (0.51) | BTKEGFRBMXITK | |
| SCHEMBL24083391 | 0.73 | BTK (0.56) | BTKEGFRTECBMXITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3409672-B1 | PARAZOLE CONDENSED-RING DERIVATIVES AND PREPARATION METHOD THEREOF AND APPLICATION THEREOF IN TREATMENT OF CANCERS, INFLAMMATION AND IMMUNE DISEASES | BEIJING INNOCARE PHARMA TECH CO LTD (CN) | 2021-12-08 | — | — | EP | disclosed |