Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | TEC | P42680 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | BMX | P51813 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24083366 | 0.85 | BTK (0.70) | BTKEGFRTECITK | |
| SCHEMBL19202673 | 0.84 | DRD2 (0.44) | BTKDRD2DRD4DRD3HRH3 | |
| SCHEMBL24083370 | 0.84 | BTK (0.51) | BTKEGFRTECBMXITK | |
| SCHEMBL19202651 | 0.81 | BTK (0.74) | BTKEGFRTECHRH3 | |
| SCHEMBL19203239 | 0.80 | BTK (0.64) | BTKEGFRTECBMXITK | |
| SCHEMBL19202397 | 0.80 | BTK (0.64) | BTKEGFRTECBMXITK | |
| SCHEMBL24083406 | 0.78 | BTK (0.59) | BTKEGFRTECBMXITK | |
| SCHEMBL19202583 | 0.75 | BTK (0.70) | BTKEGFRTECDRD3BMX | |
| SCHEMBL24083391 | 0.73 | BTK (0.56) | BTKEGFRTECBMXITK | |
| SCHEMBL19202369 | 0.72 | BTK (0.70) | BTKEGFRTECDRD3BMX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017128917-A1 | PARAZOLE CONDENSED-RING DERIVATIVES AND PREPARATION METHOD THEREOF AND APPLICATION THEREOF IN TREATMENT OF CANCERS, INFLAMMATION AND IMMUNE DISEASES | 北京诺诚健华医药科技有限公司 | 2017-08-03 | — | — | WO | disclosed |