Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4137051 | 0.81 | ACHE (0.40) | HDAC1HDAC6ACHEKMT2ANISCH | |
| SCHEMBL4126437 | 0.81 | ACHE (0.40) | HDAC1HDAC6ACHEKMT2ANISCH | |
| SCHEMBL4417489 | 0.79 | MAPT (0.40) | HDAC1HDAC6ACHEKMT2ANISCH | |
| SCHEMBL11223750 | 0.78 | ALDH1A1 (0.46) | ACHEKMT2AALDH1A1MAPTTSHR | |
| SCHEMBL18680837 | 0.77 | HDAC1 (0.37) | HDAC1HDAC6ACHEKMT2ANISCH | |
| SCHEMBL13438977 | 0.77 | HDAC1 (0.34) | HDAC1HDAC6ACHENISCHDAO | |
| SCHEMBL901110 | 0.74 | SMN1; SMN2 (0.49) | HDAC1HDAC6ACHEALDH1A1MAPT | |
| SCHEMBL20408990 | 0.74 | KMT2A (0.40) | HDAC1HDAC6ACHEKMT2AALDH1A1 | |
| SCHEMBL27350577 | 0.73 | CYP3A4 (0.52) | KMT2AALDH1A1MAPT | |
| SCHEMBL28247947 | 0.73 | KDM1A (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019013981-A1 | FLUORO-CONTAINING COMPOUNDS, USE AND PREPARATION THEREOF | JIANGSU YINGKEBEITA YIYAOKEJI CO. LTD. (CN) | 2019-01-17 | — | — | WO | disclosed |
| WO-2017132173-A1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | REGENERON PHARMACEUTICALS, INC. (US) | 2017-08-03 | — | — | WO | disclosed |