Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CD44 | P16070 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15701538 | 0.91 | CD44 (0.38) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL15701548 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL25036379 | 0.83 | CD44 (0.38) | CD44GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL19203492 | 0.83 | SMN1; SMN2 (0.39) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL17083896 | 0.82 | SMN1; SMN2 (0.37) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL16448479 | 0.82 | SMN1; SMN2 (0.37) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL2756065 | 0.81 | CYP1A2 (0.38) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL19198900 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL30843769 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A | |
| SCHEMBL9074167 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP2C9CYP2C19TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655245-B2 | Oxadiazole transient receptor potential channel inhibitors | GENENTECH, INC. (US) | 2023-05-23 | — | — | US | disclosed |
| WO-2017132173-A1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | REGENERON PHARMACEUTICALS, INC. (US) | 2017-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655245-B2 | Oxadiazole transient receptor potential channel inhibitors | TRPA1, TRPV1, P2RX3 | SMN1; SMN2 1218/4885CYP2C9 640/4885CYP2C19 654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.