Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22004963 | 0.80 | PIK3CB (0.35) | PIK3CBPRKCIPIK3CAMTORKDM4E | |
| SCHEMBL20783129 | 0.79 | PIK3CB (0.40) | PIK3CBPRKCIPIK3CAMTORHRH4 | |
| SCHEMBL21958556 | 0.77 | KDM4E (0.44) | PIK3CBPRKCIPIK3CAMTORKDM4E | |
| SCHEMBL19203917 | 0.75 | PIK3CB (0.37) | PIK3CBPRKCIHRH4KDM4EAPOBEC3A | |
| SCHEMBL23937882 | 0.74 | GRM1 (0.36) | PIK3CBMAPTSMN1; SMN2DDB1CRBN | |
| SCHEMBL15091312 | 0.69 | PIK3CB (0.44) | PIK3CBPRKCIHRH4DDB1CRBN | |
| SCHEMBL30503539 | 0.69 | APP (0.34) | PIK3CBPRKCIKDM4EMAPTAPOBEC3A | |
| SCHEMBL3481120 | 0.69 | PIK3CB (0.49) | PIK3CBPRKCIPIK3CAMTORHRH4 | |
| SCHEMBL21663754 | 0.69 | XDH (0.34) | PIK3CBPRKCIKDM4EALDH1A1MAPT | |
| SCHEMBL22705056 | 0.68 | DYRK1A (0.47) | KDM4EALDH1A1MAPTMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017132474-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2017-08-03 | — | — | WO | disclosed |