Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15205408 | 1.00 | APP (0.34) | APPKDM4EMAPTRECQLNPSR1 | |
| SCHEMBL15205145 | 0.82 | APP (0.35) | APPPIK3CBPRKCIDDB1CRBN | |
| SCHEMBL22004963 | 0.80 | PIK3CB (0.35) | APPKDM4EPIK3CBPRKCIAPOBEC3A | |
| SCHEMBL26617766 | 0.79 | APP (0.33) | APPPIK3CBPRKCIDDB1CRBN | |
| SCHEMBL9285118 | 0.79 | APP (0.39) | APPPIK3CBPRKCIDDB1CRBN | |
| SCHEMBL21663754 | 0.77 | XDH (0.34) | KDM4EMAPTNPSR1PIK3CBPRKCI | |
| SCHEMBL27262490 | 0.75 | BRD4 (0.38) | KDM4EMAPTRECQLNPSR1 | |
| SCHEMBL31345628 | 0.74 | ALDH1A1 (0.47) | APPKDM4E | |
| SCHEMBL26617809 | 0.74 | ALDH1A1 (0.47) | APPKDM4E | |
| SCHEMBL17694886 | 0.72 | RPS6KA5 (0.37) | KDM4EMAPTNPSR1PIK3CBPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |