Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19204030 | 0.80 | DGAT1 (0.40) | DGAT1KLKB1PDE10ANPC1ALDH1A1 | |
| SCHEMBL19203911 | 0.79 | DGAT1 (0.41) | DGAT1KLKB1PDE10ANPC1 | |
| SCHEMBL28991151 | 0.78 | HTR2A (0.34) | DGAT1LMNASMN1; SMN2PDE10ANPC1 | |
| SCHEMBL29663899 | 0.77 | DGAT1 (0.32) | DGAT1NPC1ALDH1A1RAB9A | |
| SCHEMBL2279186 | 0.77 | DGAT1 (0.32) | DGAT1NPC1ALDH1A1RAB9A | |
| SCHEMBL20699444 | 0.76 | KMT2A (0.41) | DGAT1KLKB1LMNASMN1; SMN2NPC1 | |
| SCHEMBL30417928 | 0.75 | DGAT1 (0.32) | DGAT1LMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL2886201 | 0.75 | DGAT1 (0.32) | DGAT1LMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL22777932 | 0.74 | HTR7 (0.47) | LMNASMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL29714393 | 0.74 | HTR7 (0.47) | LMNASMN1; SMN2NPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017132474-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2017-08-03 | — | — | WO | disclosed |