Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2989825 | 0.78 | GAA (0.44) | GAATSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL31036085 | 0.78 | GAA (0.44) | GAATSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL29760183 | 0.76 | TSHR (0.48) | GAATSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL7006546 | 0.76 | TSHR (0.48) | GAATSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL21753063 | 0.75 | GAA (0.41) | GAATSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL18825060 | 0.75 | TSHR (0.42) | GAATSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL14211018 | 0.75 | GAA (0.44) | GAATSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL19204031 | 0.74 | ALDH1A1 (0.41) | GAATSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL25337052 | 0.74 | ALDH1A1 (0.47) | GAATSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL31597058 | 0.74 | ALDH1A1 (0.47) | GAATSHRALDH1A1CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017132474-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2017-08-03 | — | — | WO | disclosed |