SCHEMBL19204432

SCHEMBL19204432

O=C(O)C1CCCCCC1C(=O)NNc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
MAPT P10636 2/20 0.61
KDM4E B2RXH2 4/20 0.58
RAB9A P51151 3/20 0.57
LMNA P02545 1/20 0.57
L3MBTL1 Q9Y468 2/20 0.54
GRK2 P25098 1/20 0.54
CASP6 P55212 1/20 0.54
CASP8 Q14790 1/20 0.54
CTDSP1 Q9GZU7 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
FNTA P49354 1/20 0.54
FNTB P49356 1/20 0.54
APEX1 P27695 1/20 0.54
TAAR1 Q96RJ0 2/20 0.52
ALDH1A1 P00352 2/20 0.52
CYP2C19 P33261 1/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19204433 1.00 GAA (0.65) GAASMN1; SMN2MAPTKDM4ERAB9A
SCHEMBL22017807 1.00 GAA (0.65) GAASMN1; SMN2MAPTKDM4ERAB9A
SCHEMBL19204430 1.00 GAA (0.65) GAASMN1; SMN2MAPTKDM4ERAB9A
SCHEMBL19204353 0.98 GAA (0.67) GAASMN1; SMN2MAPTKDM4ERAB9A
SCHEMBL21160883 0.98 GAA (0.67) GAASMN1; SMN2MAPTKDM4ERAB9A
SCHEMBL21160882 0.82 GAA (0.58) GAASMN1; SMN2MAPTKDM4ERAB9A
SCHEMBL22017754 0.82 GAA (0.51) GAASMN1; SMN2MAPTKDM4ERAB9A
SCHEMBL3600320 0.81 GAA (0.71) GAASMN1; SMN2MAPTKDM4ELMNA
SCHEMBL3605433 0.81 GAA (0.71) GAASMN1; SMN2MAPTKDM4ELMNA
SCHEMBL7431354 0.81 HPGD (0.69) GAASMN1; SMN2RAB9ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662147-B2 Phenylhydrazine/anhydride adducts and anaerobic curable compositions using same Henkel IP & Holding GmbH (DE) 2020-05-26 US disclosed
US-20170217879-A1 PHENYLHYDRAZINE/ANHYDRIDE ADDUCTS AND ANAEROBIC CURABLE COMPOSITIONS USING SAME HENKEL AG & CO. KGAA (DE) 2017-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662147-B2 Phenylhydrazine/anhydride adducts and anaerobic curable compositions using same AHCY, BAP1, GLO1 GAA 2944/4885SMN1; SMN2 2004/4885MAPT 2656/4885
US-20170217879-A1 PHENYLHYDRAZINE/ANHYDRIDE ADDUCTS AND ANAEROBIC CURABLE COMPOSITIONS USING SAME AHCY, BAP1, GLO1 GAA 2944/4885SMN1; SMN2 2004/4885MAPT 2656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.