Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3778175 | 0.82 | CES2 (0.40) | ALDH1A1ALOX15LMNAHSD17B10TSHR | |
| SCHEMBL16465224 | 0.80 | ALDH1A1 (0.37) | ALDH1A1ALOX15LMNAHSD17B10MGAM | |
| SCHEMBL3782518 | 0.77 | SOAT1 (0.44) | ALDH1A1ALOX15LMNAHSD17B10MGAM | |
| SCHEMBL21004556 | 0.77 | ALDH1A1 (0.35) | ALDH1A1ALOX15TDP1LMNAHSD17B10 | |
| SCHEMBL223479 | 0.76 | ALDH1A1 (0.50) | ALDH1A1ALOX15LMNAHSD17B10TSHR | |
| SCHEMBL125139 | 0.75 | ALDH1A1 (0.40) | ALDH1A1ALOX15LMNAHSD17B10MGAM | |
| SCHEMBL27881486 | 0.74 | ALDH1A1 (0.33) | ALDH1A1ALOX15LMNAHSD17B10CYP3A4 | |
| SCHEMBL28081545 | 0.74 | ALDH1A1 (0.39) | ALDH1A1ALOX15LMNAHSD17B10MGAM | |
| SCHEMBL16046285 | 0.70 | TDP1 (0.37) | ALDH1A1ALOX15TDP1CYP3A4TSHR | |
| SCHEMBL30870369 | 0.70 | ALDH1A1 (0.43) | ALDH1A1ALOX15LMNAHSD17B10MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133670-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |