Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.67 |
| ▸ | FBP1 | P09467 | 1/20 | 0.64 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.62 |
| ▸ | ABL1 | P00519 | 1/20 | 0.62 |
| ▸ | RET | P07949 | 1/20 | 0.62 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.62 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.61 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906958 | 0.94 | FBP1 (0.73) | EGFRFBP1ERBB2ABL1RET | |
| SCHEMBL185039 | 0.92 | FBP1 (0.75) | EGFRFBP1ERBB2ABL1RET | |
| SCHEMBL29623565 | 0.92 | FBP1 (0.75) | EGFRFBP1ERBB2ABL1RET | |
| SCHEMBL13606740 | 0.91 | EGFR (0.70) | EGFRERBB2EPHA2KDREPHB4 | |
| SCHEMBL29623554 | 0.91 | EGFR (0.70) | EGFRERBB2EPHA2KDREPHB4 | |
| SCHEMBL185864 | 0.91 | EGFR (0.70) | EGFRERBB2EPHA2KDREPHB4 | |
| SCHEMBL231729 | 0.91 | EGFR (0.70) | EGFRERBB2EPHA2KDREPHB4 | |
| SCHEMBL7219629 | 0.90 | EGFR (0.72) | EGFRERBB2 | |
| SCHEMBL5223991 | 0.90 | EGFR (0.72) | EGFRERBB2 | |
| SCHEMBL1446628 | 0.90 | EGFR (0.65) | EGFRFBP1ERBB2KDREPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2326374-A1 | INHALER | Boehringer Ingelheim International GmbH (DE) | 2011-06-01 | — | — | EP | disclosed |