SCHEMBL19205765

SCHEMBL19205765

C=C(C)C.O=S(=O)(O)C=Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HTT P42858 1/20 0.46
PPARG P37231 5/20 0.46
LMNA P02545 3/20 0.46
NFE2L2 Q16236 2/20 0.46
TSHR P16473 1/20 0.42
CYP3A4 P08684 1/20 0.42
KMT2A Q03164 1/20 0.41
GAA P10253 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HDAC3 O15379 1/20 0.41
TNKS O95271 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL8916077 0.91 TDP1 (0.47) GLATDP1HTTPPARGLMNA
Methacrylic Acid SCHEMBL19856372 0.91 TDP1 (0.47) GLATDP1HTTPPARGLMNA
SCHEMBL10777428 0.91 HTT (0.43) GLATDP1HTTPPARGLMNA
SCHEMBL20474516 0.91 HTT (0.43) GLATDP1HTTPPARGLMNA
Ethylene SCHEMBL131455 0.90 PPARG (0.50) HTTPPARGLMNANFE2L2TSHR
Formaldehyde SCHEMBL10338470 0.90 PPARG (0.50) HTTPPARGLMNANFE2L2TSHR
SCHEMBL15001 0.90 PPARG (0.53) GLATDP1HTTPPARGLMNA
SCHEMBL2496181 0.90 PPARG (0.53) GLATDP1HTTPPARGLMNA
SCHEMBL1201904 0.90 PPARG (0.53) GLATDP1HTTPPARGLMNA
SCHEMBL7095329 0.90 PPARG (0.43) GLATDP1HTTPPARGLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10104891-B2 Fused 11-membered compounds and agricultural/horticultural fungicides containing them SDS BIOTECH K.K. (JP) 2018-10-23 US disclosed
US-20180235225-A1 FUSED 11-MEMBERED COMPOUNDS AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING THEM BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2018-08-23 US disclosed
US-9980487-B2 Fused 11-membered compounds and agricultural/horticultural fungicides containing them SDS BIOTECH K.K. (JP) 2018-05-29 US disclosed
US-20170231226-A1 FUSED 11-MEMBERED COMPOUNDS AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING THEM SDS BIOTECH K.K. (JP) 2017-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170231226-A1 FUSED 11-MEMBERED COMPOUNDS AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING THEM CYP51A1, CYP4Z1, ERG28 GLA 2900/4885TDP1 2514/4885HTT 894/4885
US-10104891-B2 Fused 11-membered compounds and agricultural/horticultural fungicides containing them CYP51A1, CYP4Z1, ERG28 GLA 2900/4885TDP1 2514/4885HTT 894/4885
US-20180235225-A1 FUSED 11-MEMBERED COMPOUNDS AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING THEM CYP51A1, CYP4Z1, ERG28 GLA 2900/4885TDP1 2514/4885HTT 894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.