SCHEMBL19205829

SCHEMBL19205829

c1ccc(OOc2cccc(Oc3ccccc3)c2Oc2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.46
HRH1 P35367 1/20 0.44
LTA4H P09960 2/20 0.44
TSHR P16473 2/20 0.44
ALDH1A1 P00352 2/20 0.43
HPGD P15428 1/20 0.43
KMT2A Q03164 2/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
CTNNB1 P35222 1/20 0.40
KDM4E B2RXH2 1/20 0.39
GLA P06280 1/20 0.39
MAPT P10636 1/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A4 P31645 2/20 0.39
RIPK1 Q13546 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KDM1A O60341 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9780873 0.89 LTA4H (0.55) DPP4HRH1LTA4HTSHRALDH1A1
SCHEMBL10771806 0.88 DPP4 (0.46) DPP4HRH1LTA4HTSHRALDH1A1
SCHEMBL9273369 0.87 TSHR (0.52) DPP4HRH1LTA4HTSHRALDH1A1
SCHEMBL9275082 0.85 TSHR (0.50) DPP4HRH1LTA4HTSHRALDH1A1
SCHEMBL11816942 0.85 LTA4H (0.57) DPP4HRH1LTA4HTSHRALDH1A1
SCHEMBL28416915 0.85 TSHR (0.50) DPP4HRH1LTA4HTSHRALDH1A1
SCHEMBL10756887 0.83 MAOB (0.48) DPP4HRH1LTA4HTSHRALDH1A1
SCHEMBL19326666 0.82 LTA4H (0.52) DPP4HRH1LTA4HTSHRALDH1A1
SCHEMBL9279528 0.81 LTA4H (0.52) DPP4LTA4HTSHRALDH1A1HPGD
SCHEMBL8653148 0.78 LTA4H (0.65) LTA4HTSHRALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10596727-B2 Process for manufacturing a densified polymer powder, and process of melt processing a densified polymer powder SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-03-24 US disclosed
EP-3215334-B1 PROCESS FOR MANUFACTURING A DENSIFIED POLYMER POWDER COMPRISING AN INTERFACIAL POLYCARBONATE SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-07-03 EP disclosed
US-20170232640-A1 PROCESS FOR MANUFACTURING A DENSIFIED POLYMER POWDER, AND PROCESS OF MELT POLYMERIZING A DENSIFIED POLYMER POWDER SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-08-17 US disclosed