SCHEMBL8653148

SCHEMBL8653148

Oc1ccc(Oc2cccc(Oc3ccccc3)c2Oc2ccc(O)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.65
NR1H2 P55055 1/20 0.65
BAX Q07812 1/20 0.65
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
ALDH1A1 P00352 2/20 0.46
HPGD P15428 1/20 0.46
CAMK2A Q9UQM7 1/20 0.44
CTNNB1 P35222 1/20 0.43
LMNA P02545 2/20 0.42
CYP1A2 P05177 1/20 0.42
PTGS1 P23219 1/20 0.42
SLC6A2 P23975 1/20 0.42
CYP2C19 P33261 1/20 0.42
PTGS2 P35354 1/20 0.42
SLC6A3 Q01959 1/20 0.42
HIF1A Q16665 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11816942 0.87 LTA4H (0.57) LTA4HNR1H2BAXKMT2AALDH1A1
SCHEMBL9588305 0.87 LTA4H (0.77) LTA4HNR1H2BAXKMT2AMEN1
SCHEMBL9780873 0.87 LTA4H (0.55) LTA4HNR1H2BAXKMT2AALDH1A1
SCHEMBL9273369 0.85 TSHR (0.52) LTA4HNR1H2BAXKMT2AALDH1A1
SCHEMBL2196671 0.84 NCOA1 (0.51) LTA4HNR1H2BAXKMT2AMEN1
SCHEMBL28416915 0.83 TSHR (0.50) LTA4HKMT2AALDH1A1HPGDCTNNB1
SCHEMBL9275082 0.83 TSHR (0.50) LTA4HKMT2AALDH1A1HPGDCTNNB1
SCHEMBL4211500 0.83 LTA4H (0.68) LTA4HNR1H2BAXKMT2AMEN1
SCHEMBL982183 0.82 ALDH1A1 (0.47) LTA4HNR1H2BAXKMT2AALDH1A1
SCHEMBL10756887 0.81 MAOB (0.48) LTA4HKMT2AMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863926-A1 A PROCESS FOR THE PRODUCTION OF CYANATE ESTER RESINS HAVING UNIQUE COMPOSITION AlliedSignal Incorporated (US) 1998-09-16 EP disclosed
WO-1997019970-A1 A PROCESS FOR THE PRODUCTION OF CYANATE ESTER RESINS HAVING UNIQUE COMPOSITION ALLIEDSIGNAL INC. (US) 1997-06-05 WO disclosed
EP-0670856-A1 THERMOSETTABLE COMPOSITION CONTAINING MESOGENIC MOIETIES THE DOW CHEMICAL COMPANY (US) 1995-09-13 EP disclosed
WO-1994012556-A2 THERMOSETTABLE COMPOSITION CONTAINING DISCOTIC MESOGENIC MOIETIES THE DOW CHEMICAL COMPANY (US) 1994-06-09 WO disclosed