Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29489517 | 1.00 | KDM4E (0.33) | KDM4ENPC1MAPTALDH1A1PRMT6 | |
| SCHEMBL18915996 | 0.90 | — | — | |
| SCHEMBL19240683 | 0.85 | NPC1 (0.32) | NPC1MAPTPRMT6MCHR1 | |
| SCHEMBL17494910 | 0.84 | DDR1 (0.32) | — | |
| SCHEMBL17494927 | 0.81 | — | — | |
| SCHEMBL20165440 | 0.80 | POLB (0.42) | NPC1MAPTPRMT6 | |
| SCHEMBL22779591 | 0.77 | PDE10A (0.32) | PRMT6 | |
| SCHEMBL17640464 | 0.76 | PDE2A (0.32) | — | |
| SCHEMBL18915171 | 0.75 | CNR2 (0.33) | — | |
| SCHEMBL18916013 | 0.75 | DDR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180341-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-04-27 | — | — | EP | disclosed |
| US-10450311-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-22 | — | — | US | disclosed |
| US-10450311-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-22 | — | — | US | disclosed |
| US-20180334456-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-11-22 | — | — | US | disclosed |
| US-10005775-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS, AG (CH) | 2018-06-26 | — | — | US | disclosed |
| US-10005775-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS, AG (CH) | 2018-06-26 | — | — | US | disclosed |
| US-10005775-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS, AG (CH) | 2018-06-26 | — | — | US | disclosed |
| US-20170233389-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-17 | — | — | US | disclosed |
| US-20170233389-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-17 | — | — | US | disclosed |
| US-20170233389-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233389-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTM1 | KDM4E 2839/4885NPC1 2921/4885MAPT 797/4885 |
| US-10005775-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | DDT, ACHE, GSTM1 | KDM4E 2839/4885NPC1 2921/4885MAPT 797/4885 |
| US-10450311-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | DDT, ACHE, GSTM1 | KDM4E 2839/4885NPC1 2921/4885MAPT 797/4885 |
| US-20180334456-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTM1 | KDM4E 2839/4885NPC1 2921/4885MAPT 797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.