Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 3/20 | 0.71 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2026896 | 0.88 | NR3C2 (0.56) | NR3C2IDH1TRPV4FPR1FPR2 | |
| SCHEMBL1381714 | 0.83 | NR3C2 (1.00) | NR3C2LMNATDP1MAOARORC | |
| SCHEMBL29571805 | 0.83 | NR3C2 (1.00) | NR3C2LMNATDP1MAOARORC | |
| SCHEMBL20306403 | 0.82 | NR3C2 (0.73) | NR3C2IDH1TRPV4LMNAPOLB | |
| SCHEMBL18593496 | 0.81 | NR3C2 (0.77) | NR3C2PTGS2ELANE | |
| SCHEMBL19775750 | 0.81 | NR3C2 (0.67) | NR3C2IDH1LMNAPOLBCYP3A4 | |
| SCHEMBL24240598 | 0.80 | NR3C2 (0.65) | NR3C2LMNAPOLBMAOACYP2C19 | |
| SCHEMBL1380377 | 0.80 | NR3C2 (0.67) | NR3C2PTGS2MAOASMN1; SMN2 | |
| SCHEMBL2437620 | 0.80 | NR3C2 (0.78) | NR3C2PTGS2POLBTDP1NPC1 | |
| SCHEMBL1383401 | 0.79 | NR3C2 (0.78) | NR3C2PTGS2MAOASMN1; SMN2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233341-A1 | CRYSTAL OF PYRROLE DERIVATIVE AND METHOD FOR PRODUCING THE SAME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233341-A1 | CRYSTAL OF PYRROLE DERIVATIVE AND METHOD FOR PRODUCING THE SAME | NR3C2, MC2R, CRHR1 | NR3C2 1/4885IDH1 1955/4885TRPV4 2215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.