Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 16/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PNP | P00491 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Spermine SCHEMBL20873770 | 1.00 | HPRT1 (0.58) | HPRT1CYP3A4PNP | |
| SCHEMBL15078252 | 0.92 | HPRT1 (0.51) | HPRT1PNP | |
| SCHEMBL15078336 | 0.91 | HPRT1 (0.52) | HPRT1PNP | |
| SCHEMBL15078215 | 0.90 | HPRT1 (0.51) | HPRT1PNP | |
| SCHEMBL4715034 | 0.90 | HPRT1 (0.70) | HPRT1CYP3A4PNP | |
| SCHEMBL4713142 | 0.90 | HPRT1 (0.70) | HPRT1CYP3A4PNP | |
| SCHEMBL172846 | 0.90 | HPRT1 (0.70) | HPRT1CYP3A4PNP | |
| SCHEMBL15078211 | 0.88 | HPRT1 (0.54) | HPRT1PNP | |
| SCHEMBL23223572 | 0.87 | HPRT1 (0.55) | HPRT1PNP | |
| Pyrophosphoric Acid SCHEMBL15053837 | 0.86 | HPRT1 (0.66) | HPRT1CYP3A4PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10035814-B2 | Guanine analogs as telomerase substrates and telomere length affectors | GERON CORPORATION (US) | 2018-07-31 | — | — | US | disclosed |
| US-20170233419-A1 | Guanine Analogs as Telomerase Substrates and Telomere Length Affectors | BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233419-A1 | Guanine Analogs as Telomerase Substrates and Telomere Length Affectors | TERT, POT1, TERF2 | HPRT1 38/4885CYP3A4 4353/4885PNP 149/4885 |
| US-10035814-B2 | Guanine analogs as telomerase substrates and telomere length affectors | TERT, POT1, TERF2 | HPRT1 38/4885CYP3A4 4353/4885PNP 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.