SCHEMBL19206982

SCHEMBL19206982

CCCCCCCCCCCCc1cc2c3cc(CCCCCCCCCCCC)c4cc([Si](C(C)C)(C(C)C)C(C)C)sc4c3ccc2c2sc([Si](C(C)C)(C(C)C)C(C)C)cc12

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 6/20 0.33
TYR P14679 2/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX5 P09917 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GPR35 Q9HC97 1/20 0.32
HTR2A P28223 1/20 0.32
LIPG Q9Y5X9 1/20 0.31
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16319367 0.93 TLR8 (0.35) TLR8TYRMEN1TP53CYP3A4
SCHEMBL19206977 0.74 GPR35 (0.36) TLR8TYRMEN1TP53CYP3A4
SCHEMBL16375076 0.72 TLR8 (0.34) TLR8MEN1CYP3A4MAPTTSHR
SCHEMBL19206981 0.70 GPR35 (0.40) TLR8TYRMEN1TP53CYP3A4
SCHEMBL20414673 0.69 GPR35 (0.38) TLR8TYRMEN1TP53CYP3A4
SCHEMBL15497410 0.69 GPR35 (0.38) TLR8TYRMEN1TP53CYP3A4
SCHEMBL17385793 0.68 GPR35 (0.38) TLR8TYRMEN1TP53CYP3A4
SCHEMBL17385662 0.68 GPR35 (0.38) TLR8TYRMEN1TP53CYP3A4
SCHEMBL17385649 0.68 GPR35 (0.38) TLR8TYRMEN1TP53CYP3A4
SCHEMBL991334 0.66 GPR35 (0.41) TLR8TYRMEN1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10074804-B2 Picene derivative, photoelectric material, and photoelectric device ADEKA CORPORATION (JP) 2018-09-11 US disclosed
EP-3210986-A1 PICENE DERIVATIVE, PHOTOELECTRIC CONVERSION MATERIAL AND PHOTOELECTRIC CONVERSION ELEMENT Adeka Corporation (JP) 2017-08-30 EP disclosed
US-20170237011-A1 PICENE DERIVATIVE, PHOTOELECTRIC MATERIAL, AND PHOTOELECTRIC DEVICE ADEKA CORPORATION (JP) 2017-08-17 US disclosed
US-20170237011-A1 PICENE DERIVATIVE, PHOTOELECTRIC MATERIAL, AND PHOTOELECTRIC DEVICE ADEKA CORPORATION (JP) 2017-08-17 US disclosed