Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19206982 | 0.93 | TLR8 (0.33) | TLR8HTR2AGPR35ALOX5MEN1 | |
| SCHEMBL20414673 | 0.75 | GPR35 (0.38) | TLR8GPR35ALOX5MEN1TP53 | |
| SCHEMBL17385649 | 0.74 | GPR35 (0.38) | TLR8GPR35ALOX5MEN1TP53 | |
| SCHEMBL17385793 | 0.74 | GPR35 (0.38) | TLR8GPR35ALOX5MEN1TP53 | |
| SCHEMBL17385662 | 0.74 | GPR35 (0.38) | TLR8GPR35ALOX5MEN1TP53 | |
| SCHEMBL17432922 | 0.69 | GPR35 (0.36) | TLR8GPR35ALOX5MEN1TP53 | |
| SCHEMBL12925115 | 0.67 | GPR35 (0.37) | TLR8GPR35ALOX5MEN1TP53 | |
| SCHEMBL15979452 | 0.66 | GPR35 (0.38) | TLR8GPR35ALOX5MEN1TP53 | |
| SCHEMBL15977970 | 0.66 | GPR35 (0.38) | TLR8GPR35ALOX5MEN1TP53 | |
| SCHEMBL19206977 | 0.66 | GPR35 (0.36) | TLR8GPR35ALOX5MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018398-B2 | Intermediate for acenedichalcogenophene derivative and method for synthesizing same | NATIONAL UNIVERSITY OF CORPORATION HIROSHIMA UNIVERSITY (JP) | 2015-04-28 | — | — | US | disclosed |
| US-9018398-B2 | Intermediate for acenedichalcogenophene derivative and method for synthesizing same | NATIONAL UNIVERSITY OF CORPORATION HIROSHIMA UNIVERSITY (JP) | 2015-04-28 | — | — | US | disclosed |
| US-20150011780-A1 | INTERMEDIATE FOR ACENEDICHALCOGENOPHENE DERIVATIVE AND METHOD FOR SYNTHESIZING SAME | NATIONAL UNIVERSITY OF CORPORATION HIROSHIMA UNIVERSITY (JP) | 2015-01-08 | — | — | US | disclosed |
| US-20150011780-A1 | INTERMEDIATE FOR ACENEDICHALCOGENOPHENE DERIVATIVE AND METHOD FOR SYNTHESIZING SAME | NATIONAL UNIVERSITY OF CORPORATION HIROSHIMA UNIVERSITY (JP) | 2015-01-08 | — | — | US | disclosed |
| EP-2816044-A1 | INTERMEDIATE FOR ACENEDICHALCOGENOPHENE DERIVATIVE AND METHOD FOR SYNTHESIZING SAME | National University of Corporation Hiroshima University (JP) | 2014-12-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011780-A1 | INTERMEDIATE FOR ACENEDICHALCOGENOPHENE DERIVATIVE AND METHOD FOR SYNTHESIZING SAME | NAT1, CTRB2, SCO2 | TLR8 1821/4885HTR2A 3748/4885GPR35 3305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.