SCHEMBL19207399

SCHEMBL19207399

CCCCCCCCCCCCCCCCOc1nc2cc(Br)c(OCCCCCCCCCCCCCCCC)nc2cc1Br

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRA P10827 5/20 0.42
THRB P10828 5/20 0.42
TLR8 Q9NR97 2/20 0.41
CDK1 P06493 2/20 0.40
CCNB1 P14635 2/20 0.40
FAAH O00519 1/20 0.40
MGLL Q99685 1/20 0.40
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
CCNA2 P20248 1/20 0.38
CDK2 P24941 1/20 0.38
CCNA1 P78396 1/20 0.38
MAPT P10636 1/20 0.37
NR5A1 Q13285 1/20 0.37
PLA2G2A P14555 1/20 0.37
TSHR P16473 1/20 0.37
SMPD1 P17405 1/20 0.36
GPBAR1 Q8TDU6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28002627 0.74 TLR8 (0.54) TLR8FAAHMGLLPPARGPPARA
SCHEMBL1690054 0.73 CDK1 (0.41) TLR8CDK1CCNB1FAAHMGLL
SCHEMBL2745052 0.73 CDK1 (0.41) TLR8CDK1CCNB1FAAHMGLL
SCHEMBL1690020 0.73 FAAH (0.44) TLR8CDK1CCNB1FAAHMGLL
SCHEMBL7944727 0.73 CDK1 (0.41) TLR8CDK1CCNB1FAAHMGLL
SCHEMBL2745417 0.73 CDK1 (0.41) TLR8CDK1CCNB1FAAHMGLL
SCHEMBL7778785 0.73 CDK1 (0.41) TLR8CDK1CCNB1FAAHMGLL
SCHEMBL2744659 0.73 CDK1 (0.41) TLR8CDK1CCNB1FAAHMGLL
SCHEMBL2745072 0.73 CDK1 (0.41) TLR8CDK1CCNB1FAAHMGLL
SCHEMBL2745113 0.73 CDK1 (0.41) TLR8CDK1CCNB1FAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11603431-B2 Organic semiconductors Raynergy Tek Incorporation (TW) 2023-03-14 US disclosed
EP-3411374-B9 [1,5]NAPHTHYRIDINE COMPOUNDS AND POLYMERS AS SEMICONDUCTORS RAYNERGY TEK INC (TW) 2023-01-11 EP disclosed
EP-3411374-B1 [1,5]NAPHTHYRIDINE COMPOUNDS AND POLYMERS AS SEMICONDUCTORS RAYNERGY TEK INC (TW) 2022-08-10 EP disclosed
US-20190040188-A1 ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2019-02-07 US disclosed
EP-3411374-A1 [1,5]NAPHTHYRIDINE COMPOUNDS AND POLYMERS AS SEMICONDUCTORS Merck Patent GmbH (DE) 2018-12-12 EP disclosed
WO-2017133752-A1 [1,5]NAPHTHYRIDINE COMPOUNDS AND POLYMERS AS SEMICONDUCTORS MERCK PATENT GMBH (DE) 2017-08-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190040188-A1 ORGANIC SEMICONDUCTORS OCIAD2, OCIAD1, PPOX THRA 4698/4885THRB 4754/4885TLR8 1680/4885
US-11603431-B2 Organic semiconductors OCIAD2, OCIAD1, PPOX THRA 4698/4885THRB 4754/4885TLR8 1680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.