SCHEMBL1920752

SCHEMBL1920752

Oc1ccccc1Nc1ccccc1Nc1ccccc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 2/20 0.52
KDM4E B2RXH2 5/20 0.50
MAPT P10636 5/20 0.50
HPGD P15428 4/20 0.50
LMNA P02545 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
POLB P06746 3/20 0.50
ALDH1A1 P00352 3/20 0.50
BLM P54132 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
NPC1 O15118 2/20 0.50
CA12 O43570 2/20 0.50
CA2 P00918 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
ALOX15 P16050 2/20 0.50
HSD17B10 Q99714 2/20 0.50
GMNN O75496 1/20 0.50
EGFR P00533 1/20 0.50
FYN P06241 1/20 0.50
CA3 P07451 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL304891 0.97 CXCR2 (0.54) CXCR2KDM4EMAPTHPGDLMNA
SCHEMBL10741108 0.88 CXCR2 (0.63) CXCR2KDM4EMAPTHPGDLMNA
SCHEMBL1920750 0.83 CXCR2 (0.59) CXCR2KDM4EMAPTHPGDLMNA
SCHEMBL9118423 0.83 MAPT (0.56) CXCR2KDM4EMAPTHPGDLMNA
SCHEMBL22584770 0.83 CXCR2 (0.53) CXCR2KDM4EMAPTHPGDLMNA
SCHEMBL6883396 0.83 HTT (0.52) CXCR2KDM4EMAPTHPGDLMNA
SCHEMBL11554645 0.81 CXCR2 (0.57) CXCR2KDM4EMAPTHPGDLMNA
SCHEMBL29720861 0.81 CXCR2 (0.68) CXCR2KDM4EMAPTHPGDLMNA
SCHEMBL1008928 0.81 CXCR2 (0.68) CXCR2KDM4EMAPTHPGDLMNA
Hydrochloric Acid SCHEMBL9121083 0.81 MAPT (0.54) CXCR2KDM4EMAPTHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed