SCHEMBL1920750

SCHEMBL1920750

Oc1ccccc1Nc1ccc(Nc2ccccc2O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 2/20 0.59
MAPT P10636 9/20 0.46
KDM4E B2RXH2 6/20 0.46
ALOX15 P16050 4/20 0.46
HSD17B10 Q99714 4/20 0.46
HPGD P15428 4/20 0.46
BLM P54132 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
TP53 P04637 3/20 0.46
APP P05067 1/20 0.46
SNCA P37840 1/20 0.46
GAA P10253 8/20 0.46
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
TDP1 Q9NUW8 5/20 0.46
RECQL P46063 2/20 0.46
GLA P06280 1/20 0.46
ALDH1A1 P00352 5/20 0.46
MAPK1 P28482 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11000813 0.93 CXCR2 (0.63) CXCR2MAPTKDM4EALOX15HSD17B10
SCHEMBL1921886 0.93 CXCR2 (0.53) CXCR2MAPTKDM4EALOX15HSD17B10
SCHEMBL6760764 0.93 MAPT (0.55) CXCR2MAPTKDM4EALOX15HSD17B10
SCHEMBL29720861 0.92 CXCR2 (0.68) CXCR2MAPTKDM4EALOX15HSD17B10
SCHEMBL1008928 0.92 CXCR2 (0.68) CXCR2MAPTKDM4EALOX15HSD17B10
SCHEMBL27435565 0.90 CXCR2 (0.66) CXCR2MAPTKDM4EALOX15HSD17B10
SCHEMBL9566028 0.89 CXCR2 (0.50) CXCR2MAPTKDM4EALOX15HSD17B10
SCHEMBL30686692 0.89 MAPT (0.60) CXCR2MAPTKDM4EHSD17B10HPGD
SCHEMBL19185367 0.89 MAPT (0.64) CXCR2MAPTKDM4EALOX15HSD17B10
SCHEMBL28291094 0.89 CXCR2 (0.50) CXCR2MAPTKDM4EALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5270137-A None JP disclosed
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed
JP-H05270137-A COLOR FORMING RECORDING MATERIAL MITSUI PETROCHEM IND LTD 1993-10-19 JP disclosed