Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29720861 | 1.00 | CXCR2 (0.68) | CXCR2MAPTTDP1MEN1KMT2A | |
| SCHEMBL27435565 | 0.98 | CXCR2 (0.66) | CXCR2MAPTTDP1MEN1KMT2A | |
| SCHEMBL11000813 | 0.95 | CXCR2 (0.63) | CXCR2MAPTTDP1MEN1KMT2A | |
| SCHEMBL10741108 | 0.95 | CXCR2 (0.63) | CXCR2MAPTTDP1MEN1KMT2A | |
| SCHEMBL1920750 | 0.92 | CXCR2 (0.59) | CXCR2MAPTTDP1MEN1KMT2A | |
| SCHEMBL6760764 | 0.86 | MAPT (0.55) | CXCR2MAPTTDP1MEN1KMT2A | |
| SCHEMBL1921886 | 0.86 | CXCR2 (0.53) | CXCR2MAPTTDP1MEN1KMT2A | |
| SCHEMBL29165703 | 0.84 | CXCR2 (0.52) | CXCR2MAPTTDP1MEN1KMT2A | |
| SCHEMBL27294589 | 0.84 | MAPT (0.56) | CXCR2MAPTTDP1MEN1KMT2A | |
| SCHEMBL304891 | 0.84 | CXCR2 (0.54) | CXCR2MAPTTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103275769-B | High-cleanness environment-friendly alcohol ether fuel for car | LU JIAZHENG | 2015-05-13 | — | — | CN | claimed |
| US-8853207-B2 | Heterocyclic pyrazole compounds, method for preparing the same and use thereof | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2014-10-07 | — | — | US | claimed |
| CN-103703005-A | Tricyclic inhibitors of kinases | ABBOTT LAB | 2014-04-02 | — | — | CN | claimed |
| US-20130274255-A1 | HETEROCYCLIC PYRAZOLE COMPOUNDS, METHOD FOR PREPARING THE SAME AND USE THEREOF | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2013-10-17 | — | — | US | claimed |
| CN-103275769-A | High-cleanness environment-friendly alcohol ether fuel for car | LU JIAZHENG | 2013-09-04 | — | — | CN | claimed |
| CN-101790413-A | Separation membrane comprising polyethersulfone, process for production thereof, and stock solution for production of film | KAWASAKI HEAVY IND LTD | 2010-07-28 | — | — | CN | claimed |
| CN-1052000-C | Process for the preparation of alkylimidazolidone (meth)acrylateds | ATOCHEM ELF SA (FR) | 2000-05-03 | — | — | CN | claimed |
| CN-1051999-C | Process for the preparation of alkylimidazolidone (meth)acrylate(s) | ATOCHEM ELF SA (FR) | 2000-05-03 | — | — | CN | claimed |
| CN-1050353-C | Process for preparing alkylimidazolidone (meth) acrylates | ATOCHEM ELF SA (FR) | 2000-03-15 | — | — | CN | claimed |
| CN-1179419-A | Process for manufacture of alkylimidazolidone (methyl) acrylates | ATOCHEM ELF SA (FR) | 1998-04-22 | — | — | CN | claimed |
| CN-1127750-A | Process for the preparation of alkylimidazolidone (meth)acrylateds | ATOCHEM ELF SA (FR) | 1996-07-31 | — | — | CN | claimed |
| CN-1105992-A | Process for preparing alkylimidazolidone (meth) acrylates | ATOCHEM ELF SA (FR) | 1995-08-02 | — | — | CN | claimed |
| CN-1097742-A | The method for preparing alkyl imidazoline ketone (methyl) acrylate | ATOCHEM ELF SA (FR) | 1995-01-25 | — | — | CN | claimed |
| US-4696756-A | SILOXANE BLEND | TORAY SILICONE CO., LTD. (JP) | 1987-09-29 | — | — | US | claimed |
| US-4683319-A | POLYSILOXANE REACTED WITH AROMATIC AMINOPHENOL, VISCOSITY STABILIZER | TORAY SILICONE CO., LTD. (JP) | 1987-07-28 | — | — | US | claimed |
| JP-55038355-A | — | — | None | — | — | JP | disclosed |
| JP-4220442-A | — | — | None | — | — | JP | disclosed |
| US-4086405-A | ZINC OR NICKEL-CADMIUM ELECTRODES, POLYVINYL ACETAL SEPARATOR | COMPAGNIE GENERALE D'ELECTRICITE S.A. (FR) | 1978-04-25 | — | — | US | disclosed |
| US-3979411-A | FUNGICIDES, INSECTICIDE, MITICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-07 | — | — | US | disclosed |
| US-3960886-A | Substituted N-arylanilines | STERLING DRUG INC. (US) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274255-A1 | HETEROCYCLIC PYRAZOLE COMPOUNDS, METHOD FOR PREPARING THE SAME AND USE THEREOF | RET, FLT3, FGFR1 | CXCR2 434/4885MAPT 2422/4885TDP1 2062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.