SCHEMBL1920795

SCHEMBL1920795

O=[C]c1c2ccccc2cc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
HSD17B10 Q99714 4/20 0.48
CYP1A2 P05177 4/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
HPGD P15428 2/20 0.48
KDM4E B2RXH2 1/20 0.48
GLA P06280 1/20 0.48
CYP2C19 P33261 1/20 0.48
CYP3A4 P08684 1/20 0.46
HIF1A Q16665 1/20 0.46
CYP1B1 Q16678 1/20 0.46
HTR2A P28223 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
PKM P14618 1/20 0.42
RAD52 P43351 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
ERBB2 P04626 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4893709 0.91 ALDH1A1 (0.44) ALDH1A1HSD17B10CYP1A2MEN1KMT2A
SCHEMBL9410288 0.84 ALDH1A1 (0.38) ALDH1A1HSD17B10CYP1A2MEN1KMT2A
SCHEMBL14165957 0.81 ALDH1A1 (0.48) ALDH1A1HSD17B10CYP1A2MEN1KMT2A
SCHEMBL3245816 0.81 HPRT1 (0.37) ALDH1A1HSD17B10CYP1A2MEN1KMT2A
SCHEMBL3242745 0.81 CYP2A6 (0.41) ALDH1A1HSD17B10CYP1A2MEN1KMT2A
SCHEMBL10996327 0.80 ALDH1A1 (0.38) ALDH1A1HSD17B10CYP1A2MEN1KMT2A
SCHEMBL6280209 0.78 CTRB1 (0.41) ALDH1A1HSD17B10CYP1A2MEN1KMT2A
SCHEMBL32211 0.77 ALDH1A1 (0.58) ALDH1A1HSD17B10CYP1A2MEN1KMT2A
SCHEMBL5012529 0.77 ALDH1A1 (0.44) ALDH1A1HSD17B10CYP1A2MEN1KMT2A
SCHEMBL1610724 0.77 ALDH1A1 (0.44) ALDH1A1HSD17B10CYP1A2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002083606-A1 A LINKER SYSTEM FOR THE SYNTHESIS AND SCREENING OF COMBINATORIAL LIBRARIES OF POLYAMINE DERIVATIVES ON WATER COMPATIBLE SUPPORTS UNIVERSITY OF ALBERTA (CA) 2002-10-24 WO claimed
WO-1984000297-A1 USE OF CALMODULIN BINDING DRUGS AS VAGINAL CONTRACEPTIVES UNIV GEORGIA RES FOUND (US) 1984-02-02 WO claimed
US-4314936-A BY MEASUREM,ENT OF FLUORESENCE YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1982-02-09 US claimed
CN-116813979-A Nucleating agent, synthetic resin composition containing same, and molded article thereof 株式会社ADEKA 2023-09-29 CN disclosed
CN-112839988-B Nucleating agent, synthetic resin composition containing same, and molded article thereof 株式会社ADEKA 2023-06-06 CN disclosed
US-20220413384-A1 PHOTOSENSITIVE COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-12-29 US disclosed
US-20210395209-A1 NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF ADEKA CORPORATION (JP) 2021-12-23 US disclosed
EP-3858909-A1 NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF ADEKA CORPORATION (JP) 2021-08-04 EP disclosed
CN-112839988-A Nucleating agent, synthetic resin composition containing same, and molded article thereof 株式会社ADEKA 2021-05-25 CN disclosed
CN-111187220-A Trifluoromethyl pyrimidine derivative containing Schiff base structural unit and preparation method and application thereof 郑州大学 2020-05-22 CN disclosed
WO-2020067144-A1 NUCLEATING AGNET, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF 株式会社ADEKA 2020-04-02 WO disclosed
EP-0542117-B1 Process for the preparation of aryle esters of chloroformic acid BASF AG (DE) 1995-09-13 EP disclosed
EP-0528854-B1 FLUOROGENIC PEPTIDES AND THEIR USE IN THE DETERMINATION OF ENZYMATIC ACTIVITIES CARLSBERG AS (DK) 1994-12-28 EP disclosed
US-5274164-A Preparation of aryl chloroformates BASF AKTIENGESELLSCHAFT (DE) 1993-12-28 US disclosed
EP-0542117-A1 Process for the preparation of aryle esters of chloroformic acid BASF Aktiengesellschaft (DE) 1993-05-19 EP disclosed
EP-0542132-A1 Process for the preparation of aryle esters of chloroformic acid BASF Aktiengesellschaft (DE) 1993-05-19 EP disclosed
EP-0528854-A1 FLUOROGENIC PEPTIDES AND THEIR USE IN THE DETERMINATION OF ENZYMATIC ACTIVITIES. CARLSBERG AS (DK) 1993-03-03 EP disclosed
WO-1991016336-A1 FLUOROGENIC PEPTIDES AND THEIR USE IN THE DETERMINATION OF ENZYMATIC ACTIVITIES CARLSBERG A/S (DK) 1991-10-31 WO disclosed
US-4933355-A ALDOSE REDUCTASE INHIBITORS SANKYO COMPANY LIMITED (JP) 1990-06-12 US disclosed
US-4314936-A BY MEASUREM,ENT OF FLUORESENCE YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1982-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210395209-A1 NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF NOC2L, RIF1, NAP1L1 ALDH1A1 2699/4885HSD17B10 3823/4885CYP1A2 3026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.