Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19935743 | 1.00 | KMT2A (0.49) | KMT2AKDM4EL3MBTL1GAAJAK2 | |
| SCHEMBL19209038 | 0.86 | GAA (0.44) | KMT2AGAAJAK2JAK1TYK2 | |
| SCHEMBL19209037 | 0.86 | GAA (0.44) | KMT2AGAAJAK2JAK1TYK2 | |
| SCHEMBL16345869 | 0.85 | GAA (0.48) | KMT2AL3MBTL1GAAJAK2JAK1 | |
| SCHEMBL16583355 | 0.84 | MEN1 (0.44) | KMT2AKDM4EGAAJAK2JAK1 | |
| SCHEMBL19576319 | 0.84 | GAA (0.43) | KMT2AGAAJAK2JAK1TYK2 | |
| SCHEMBL16583403 | 0.82 | LMNA (0.48) | KMT2AGAAJAK2JAK1TYK2 | |
| SCHEMBL2608534 | 0.81 | KMT2A (0.61) | KMT2AKDM4EL3MBTL1GAAMEN1 | |
| SCHEMBL18188681 | 0.80 | RAB9A (0.40) | KMT2AKDM4EGAAJAK2JAK1 | |
| SCHEMBL18188684 | 0.80 | RAB9A (0.40) | KMT2AKDM4EGAAJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017191608-A1 | NOVEL PROCESS FOR PREPARATION OF IDELALISIB | LAURUS LABS LIMITED (IN) | 2017-11-09 | — | — | WO | disclosed |