Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19209441 | 0.94 | MTNR1A (0.46) | MTNR1AMTNR1BCYP4F2CYP4A11PPARG | |
| SCHEMBL19209418 | 0.84 | PPARG (0.44) | MTNR1AMTNR1BPPARGPTPN1ALDH1A1 | |
| SCHEMBL1892714 | 0.82 | MTNR1A (0.47) | MTNR1AMTNR1BCYP4F2CYP4A11PPARG | |
| SCHEMBL35843127 | 0.82 | MTNR1A (0.47) | MTNR1AMTNR1BCYP4F2CYP4A11PPARG | |
| SCHEMBL19257206 | 0.82 | FFAR1 (0.53) | MTNR1AMTNR1BPPARGFFAR1 | |
| SCHEMBL19257207 | 0.80 | MTNR1A (0.45) | MTNR1AMTNR1BCYP4F2CYP4A11PPARG | |
| SCHEMBL12660791 | 0.80 | MTNR1A (0.43) | MTNR1AMTNR1BCYP4F2CYP4A11PPARG | |
| SCHEMBL1822788 | 0.80 | CYP4F2 (0.48) | MTNR1AMTNR1BCYP4F2CYP4A11PPARG | |
| SCHEMBL19209477 | 0.80 | POLB (0.45) | CYP4F2CYP4A11PPARGALDH1A1TDP1 | |
| SCHEMBL1823881 | 0.78 | MTNR1A (0.44) | MTNR1AMTNR1BPPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134146-A1 | GPBP INHIBITORS AND USES AND SCALEABLE SYNTHESIS THEREOF | FIBROSTATIN, S.L. (ES) | 2017-08-10 | — | — | WO | disclosed |