Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | HRH2 | P25021 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19209427 | 0.94 | PPARG (0.44) | PPARGHRH2HRH1TLR8TLR7 | |
| SCHEMBL19209453 | 0.89 | FFAR1 (0.45) | MAPK14 | |
| SCHEMBL19209481 | 0.84 | MTNR1A (0.48) | PPARGMTNR1AMTNR1BPTPN1ALDH1A1 | |
| SCHEMBL19209490 | 0.83 | FFAR1 (0.47) | MAPK14MTNR1AMTNR1B | |
| SCHEMBL35843127 | 0.81 | MTNR1A (0.47) | PPARGMTNR1AMTNR1BPTPN1ALDH1A1 | |
| SCHEMBL1892714 | 0.81 | MTNR1A (0.47) | PPARGMTNR1AMTNR1BPTPN1ALDH1A1 | |
| SCHEMBL19209500 | 0.79 | XDH (0.46) | PPARGMTNR1AMTNR1BPTPN1ALDH1A1 | |
| SCHEMBL19209441 | 0.78 | MTNR1A (0.46) | PPARGMTNR1AMTNR1BPTPN1ALDH1A1 | |
| SCHEMBL19257207 | 0.78 | MTNR1A (0.45) | PPARGMTNR1AMTNR1BPTPN1ALDH1A1 | |
| SCHEMBL12660791 | 0.78 | MTNR1A (0.43) | PPARGMTNR1AMTNR1BPTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134146-A1 | GPBP INHIBITORS AND USES AND SCALEABLE SYNTHESIS THEREOF | FIBROSTATIN, S.L. (ES) | 2017-08-10 | — | — | WO | disclosed |