Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | EIF4E | P06730 | 3/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19257271 | 0.85 | IGF2BP2 (0.47) | IGF2BP2EIF4EPTPN11FFAR4FFAR1 | |
| SCHEMBL19257563 | 0.82 | PTPN11 (0.49) | IGF2BP2PTPN11FFAR4FFAR1SMN1; SMN2 | |
| SCHEMBL27636056 | 0.79 | IGF2BP2 (0.59) | IGF2BP2EIF4EFFAR4FFAR1SMN1; SMN2 | |
| SCHEMBL3939209 | 0.79 | MCL1 (0.59) | MCL1S1PR1PTPN11FFAR4AKR1C2 | |
| SCHEMBL20594547 | 0.78 | IGF2BP2 (0.54) | IGF2BP2EIF4EPTPN11SMN1; SMN2AKR1C2 | |
| SCHEMBL14820473 | 0.78 | EIF4E (0.74) | EIF4E | |
| SCHEMBL6676508 | 0.76 | FFAR4 (0.46) | FFAR4PDK2PPARGPPARASCN5A | |
| SCHEMBL14126262 | 0.75 | AKR1C3 (0.54) | IGF2BP2PTPN11FFAR4AKR1C2PDK2 | |
| SCHEMBL5937086 | 0.75 | AKR1C2 (0.52) | IGF2BP2EIF4EFFAR4FFAR1SMN1; SMN2 | |
| SCHEMBL2326026 | 0.74 | IGF2BP2 (0.49) | IGF2BP2FFAR4AKR1C2AKR1C1SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134146-A1 | GPBP INHIBITORS AND USES AND SCALEABLE SYNTHESIS THEREOF | FIBROSTATIN, S.L. (ES) | 2017-08-10 | — | — | WO | disclosed |