Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | GPR3 | P46089 | 3/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29618444 | 0.83 | GPR3 (0.47) | FFAR4GPR3MAPK8MAPK10PPARG | |
| SCHEMBL965069 | 0.81 | CHEK1 (0.46) | FFAR4GPR3MAPK8CHEK1PPARG | |
| Hydrochloric Acid SCHEMBL7999913 | 0.80 | CHEK1 (0.45) | FFAR4GPR3MAPK8CHEK1PPARG | |
| SCHEMBL2562027 | 0.79 | BCAT2 (0.59) | FFAR4MAPK8MAPK10BCAT2CHEK1 | |
| SCHEMBL12569554 | 0.78 | CHEK1 (0.46) | FFAR4GPR3MAPK8CHEK1KDM4E | |
| SCHEMBL5498010 | 0.78 | BCAT2 (0.54) | BCAT2CHEK1SCN9A | |
| SCHEMBL4517767 | 0.76 | BCAT2 (0.51) | FFAR4BCAT2CHRM5CHEK1SCN5A | |
| SCHEMBL19209484 | 0.76 | MCL1 (0.50) | FFAR4PPARGPPARAPDK2SCN5A | |
| SCHEMBL7890733 | 0.75 | ESR2 (0.51) | MAPK10BCAT2CHEK1ESR1KDM4E | |
| SCHEMBL7033171 | 0.75 | BCAT2 (0.49) | BCAT2CHEK1PPARGKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427705-A2 | INSECTICIDAL DIAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003026415-A2 | INSECTICIDAL DIAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |