Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.49 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19257271 | 0.88 | IGF2BP2 (0.47) | PTPN11IGF2BP2MMP2MMP3FFAR1 | |
| SCHEMBL20594547 | 0.82 | IGF2BP2 (0.54) | PTPN11IGF2BP2SMN1; SMN2DHODHMRGPRX4 | |
| SCHEMBL19209484 | 0.82 | MCL1 (0.50) | PTPN11IGF2BP2MMP2MMP3FFAR1 | |
| SCHEMBL27636056 | 0.78 | IGF2BP2 (0.59) | IGF2BP2FFAR1FFAR4SMN1; SMN2DHODH | |
| SCHEMBL14126262 | 0.77 | AKR1C3 (0.54) | PTPN11IGF2BP2FFAR4MRGPRX4PPARG | |
| SCHEMBL18414391 | 0.74 | BCL2 (0.58) | PTPN11BCL2SMN1; SMN2PPARG | |
| SCHEMBL19257233 | 0.73 | SMN1; SMN2 (0.63) | PTPN11MMP2MMP3FFAR1SMN1; SMN2 | |
| SCHEMBL9511283 | 0.73 | LTB4R (0.53) | PTPN11BCL2FFAR1SMN1; SMN2DHODH | |
| SCHEMBL13099463 | 0.73 | BCL2 (0.51) | BCL2MRGPRX4 | |
| SCHEMBL22109071 | 0.72 | KDM4E (0.56) | IGF2BP2DHODHMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134146-A1 | GPBP INHIBITORS AND USES AND SCALEABLE SYNTHESIS THEREOF | FIBROSTATIN, S.L. (ES) | 2017-08-10 | — | — | WO | disclosed |