Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19209590 | 0.78 | MAOB (0.46) | MAOBMAOAALDH1A1ADORA2AADORA1 | |
| SCHEMBL2859753 | 0.76 | NPSR1 (0.43) | POLBNPSR1ALDH1A1ADORA2AADORA1 | |
| SCHEMBL2849310 | 0.75 | POLB (0.42) | POLBNPSR1CYP3A4ALDH1A1ADORA2A | |
| SCHEMBL3323333 | 0.72 | MAOB (0.47) | MAOBLOXL2CYP3A4CYP2A6MAOA | |
| SCHEMBL26615234 | 0.71 | CYP3A4 (0.43) | MAOBLOXL2CYP3A4CYP2A6MAOA | |
| SCHEMBL3952773 | 0.70 | TNKS (0.47) | NPSR1ALDH1A1ADORA2AKDM4E | |
| SCHEMBL19209596 | 0.69 | ACP1 (0.42) | POLBNPSR1 | |
| SCHEMBL19209595 | 0.69 | NPSR1 (0.38) | POLBNPSR1ADORA2AADORA1KDM4E | |
| SCHEMBL19209588 | 0.68 | ALDH1A1 (0.35) | SLC2A1LOXL2ALDH1A1KDM4E | |
| SCHEMBL15473209 | 0.68 | NPSR1 (0.44) | SLC2A1NPSR1ALDH1A1KDM4EHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136642-A1 | ANTIBIOTIC COMPOSITIONS | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017136642-A1 | ANTIBIOTIC COMPOSITIONS | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2017-08-10 | — | — | WO | disclosed |