Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | GAK | O14976 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19209595 | 0.77 | NPSR1 (0.38) | TRPA1POLBNPSR1TNKSTNKS2 | |
| SCHEMBL2859753 | 0.77 | NPSR1 (0.43) | IGF1RTRPA1POLBNPSR1 | |
| SCHEMBL2849310 | 0.76 | POLB (0.42) | ABCG2IGF1RTRPA1EPHX2POLB | |
| SCHEMBL19209583 | 0.69 | MAOB (0.39) | POLBNPSR1 | |
| SCHEMBL16481037 | 0.68 | ALDH1A1 (0.65) | ACP1ABCG2EPHX2MEN1KMT2A | |
| SCHEMBL30804591 | 0.68 | ALDH1A1 (0.65) | ACP1ABCG2EPHX2MEN1KMT2A | |
| SCHEMBL13135661 | 0.68 | KDM4E (0.57) | MEN1KMT2A | |
| SCHEMBL2855235 | 0.68 | ADRB2 (0.61) | POLBNPSR1 | |
| SCHEMBL19209593 | 0.67 | GAA (0.52) | ACP1ABCG2IGF1RGAKMEN1 | |
| SCHEMBL3952773 | 0.65 | TNKS (0.47) | MEN1KMT2ARAB9ANPSR1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136642-A1 | ANTIBIOTIC COMPOSITIONS | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017136642-A1 | ANTIBIOTIC COMPOSITIONS | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2017-08-10 | — | — | WO | disclosed |