Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GGH | Q92820 | 1/20 | 0.30 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | CPA1 | P15085 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19235724 | 0.80 | BTN3A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL19209678 | 0.80 | BTN3A1 (0.36) | TSHR | |
| SCHEMBL19209680 | 0.80 | BTN3A1 (0.36) | TSHR | |
| SCHEMBL20168386 | 0.72 | ALDH1A1 (0.42) | KDM4EALDH1A1SMN1; SMN2TSHRMME | |
| SCHEMBL20168384 | 0.72 | ALDH1A1 (0.42) | KDM4EALDH1A1SMN1; SMN2TSHRMME | |
| SCHEMBL28349285 | 0.70 | BTN3A1 (0.31) | KDM4EALDH1A1TSHR | |
| SCHEMBL28349287 | 0.70 | BTN3A1 (0.31) | KDM4EALDH1A1TSHR | |
| SCHEMBL17859365 | 0.69 | MMP1 (0.37) | KDM4EALDH1A1SMN1; SMN2GGHACE | |
| SCHEMBL19300637 | 0.69 | MMP1 (0.37) | KDM4EALDH1A1SMN1; SMN2GGHACE | |
| SCHEMBL7389186 | 0.68 | MMP1 (0.35) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709288-A | Phosphamide derivative and preparation method and application thereof | 四川海思科制药有限公司 | 2018-02-16 | — | — | CN | disclosed |
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |