Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22445341 | 0.85 | CSNK2A1 (0.32) | — | |
| SCHEMBL16962902 | 0.82 | — | — | |
| SCHEMBL2737328 | 0.73 | ALDH1A1 (0.35) | ALDH1A1GAANOS3NOS1NOS2 | |
| SCHEMBL2610824 | 0.73 | BAZ2B (0.39) | ALDH1A1LMNASMN1; SMN2GAANOS3 | |
| SCHEMBL23325440 | 0.71 | ALDH1A1 (0.31) | ALDH1A1GAANOS3NOS1NOS2 | |
| SCHEMBL8763937 | 0.71 | ALDH1A1 (0.34) | ALDH1A1LMNAGAANOS3NOS1 | |
| SCHEMBL4423855 | 0.71 | NOS3 (0.39) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8764618 | 0.71 | MAPK8 (0.32) | ALDH1A1KDM4EMEN1NPC1LMNA | |
| SCHEMBL26860413 | 0.71 | ALDH1A1 (0.31) | ALDH1A1GAANOS3NOS1NOS2 | |
| SCHEMBL2516596 | 0.71 | ALDH1A1 (0.32) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024115512-A1 | MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-06 | — | — | WO | disclosed |
| CN-108602799-B | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2021-08-03 | — | — | CN | disclosed |
| WO-2017133701-A1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2017-08-10 | — | — | WO | disclosed |