Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2968350 | 0.85 | GABRA1 (0.36) | KMT2AMEN1TP53MAPTHPGD | |
| SCHEMBL31254116 | 0.81 | PLAU (0.32) | KMT2AMEN1TP53MAPTHPGD | |
| SCHEMBL20390070 | 0.81 | GABRA1 (0.43) | KMT2AMEN1TP53MAPTHPGD | |
| SCHEMBL28634201 | 0.81 | PLAU (0.33) | KMT2AMEN1TP53MAPTHPGD | |
| SCHEMBL28553372 | 0.79 | S1PR1 (0.35) | KMT2AMEN1TP53MAPTHPGD | |
| SCHEMBL29555695 | 0.79 | S1PR1 (0.35) | KMT2AMEN1TP53MAPTHPGD | |
| SCHEMBL24805816 | 0.79 | PDE2A (0.38) | PDE2A | |
| SCHEMBL26587450 | 0.79 | PDE2A (0.38) | KMT2AGABRA1GABRB1METPDE2A | |
| SCHEMBL27841463 | 0.77 | KMT2A (0.37) | KMT2AMEN1TP53MAPTHPGD | |
| SCHEMBL18497256 | 0.75 | ALDH1A1 (0.36) | KMT2AMEN1TP53MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602799-B | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2021-08-03 | — | — | CN | disclosed |
| WO-2017133701-A1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2017-08-10 | — | — | WO | disclosed |