⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28816624 | 0.83 | RECQL (0.34) | — | |
| SCHEMBL29844749 | 0.83 | RECQL (0.34) | — | |
| SCHEMBL20519442 | 0.83 | RECQL (0.34) | — | |
| SCHEMBL23063036 | 0.79 | — | — | |
| SCHEMBL2737328 | 0.76 | ALDH1A1 (0.35) | — | |
| SCHEMBL678753 | 0.74 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL21736933 | 0.74 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL12285500 | 0.73 | — | — | |
| SCHEMBL23063285 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL22882519 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286973-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2023-09-14 | — | — | US | disclosed |
| US-20230286973-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2023-09-14 | — | — | US | disclosed |
| CN-114786673-A | CDK inhibitors and their use as medicaments | 普莱鲁德疗法有限公司 | 2022-07-22 | — | — | CN | disclosed |
| WO-2017133701-A1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2017-08-10 | — | — | WO | disclosed |