Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | GRM8 | O00222 | 2/20 | 0.51 |
| ▸ | GRM6 | O15303 | 2/20 | 0.51 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | GSR | P00390 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL2228115 | 1.00 | CYP1A2 (0.51) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Histidine SCHEMBL4356748 | 1.00 | CYP1A2 (0.51) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Histidine SCHEMBL23306565 | 1.00 | CYP1A2 (0.51) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Histidine SCHEMBL23291081 | 0.99 | CYP1A2 (0.50) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Histidine SCHEMBL5670423 | 0.95 | CYP1A2 (0.46) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Histidine SCHEMBL2730156 | 0.95 | ALOX15 (0.49) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Histidine SCHEMBL4229349 | 0.95 | CYP1A2 (0.46) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Histidine SCHEMBL2727906 | 0.95 | ALOX15 (0.49) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Histidine SCHEMBL9389369 | 0.95 | ALOX15 (0.49) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Histidine SCHEMBL17981689 | 0.95 | GRIA1 (0.46) | CYP1A2GRM8GRM6GRM7GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11285210-B2 | Buffer formulations for enhanced antibody stability | OUTLOOK THERAPEUTICS, INC. (US) | 2022-03-29 | — | — | US | disclosed |
| US-20190030163-A1 | BUFFER FORMULATIONS FOR ENHANCED ANTIBODY STABILITY | OUTLOOK THERAPEUTICS, INC. | 2019-01-31 | — | — | US | disclosed |
| EP-3411401-A1 | BUFFER FORMULATIONS FOR ENHANCED ANTIBODY STABILITY | Oncobiologics, Inc. (US) | 2018-12-12 | — | — | EP | disclosed |
| WO-2017136433-A1 | BUFFER FORMULATIONS FOR ENHANCED ANTIBODY STABILITY | ONCOBIOLOGICS, INC. (US) | 2017-08-10 | — | — | WO | disclosed |