Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GRM8 | O00222 | 2/20 | 0.46 |
| ▸ | GRM6 | O15303 | 2/20 | 0.46 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL27814600 | 1.00 | CYP1A2 (0.46) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Histidine SCHEMBL19209941 | 0.95 | CYP1A2 (0.51) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Histidine SCHEMBL2228115 | 0.95 | CYP1A2 (0.51) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Histidine SCHEMBL4356748 | 0.95 | CYP1A2 (0.51) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Histidine SCHEMBL23306565 | 0.95 | CYP1A2 (0.51) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Histidine SCHEMBL23291081 | 0.93 | CYP1A2 (0.50) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Histidine SCHEMBL27730526 | 0.91 | BLM (0.47) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Histidine SCHEMBL874923 | 0.91 | SLC7A5 (0.43) | CYP1A2GRIA1GRIA2GRIA3GRIA4 | |
| Histidine SCHEMBL874925 | 0.91 | SLC7A5 (0.43) | CYP1A2GRIA1GRIA2GRIA3GRIA4 | |
| Histidine SCHEMBL2727906 | 0.90 | ALOX15 (0.49) | CYP1A2GRM8GRM6GRM7GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170146-A1 | Novel Carboxylesterase Nucleic Acid Molecules, Proteins and Uses Thereof | WELLS FARGO BUSINESS CREDIT, INC. | 2009-07-02 | — | — | US | disclosed |
| US-20040081998-A1 | Novel carboxylesterase nucleic acid molecules, proteins and uses thereof | SILVER GARY M (US) | 2004-04-29 | — | — | US | disclosed |
| US-6664090-B1 | Use as therapeutic compositions to protect animals from hematophagous arthropod (flea) infestations | HESKA CORPORATION | 2003-12-16 | — | — | US | disclosed |
| US-6291222-B1 | ANTIBODIES; ENZYME INHIBITORS; FLEAS; GENETIC ENGINEERING | HESKA CORPORATION | 2001-09-18 | — | — | US | disclosed |
| US-6063610-A | FLEA HYDROLASE ENZYME; FOR DEVELOPMENT OF ANTIBODIES TO PREVENT PARASITIC INFECTION OF PLANT AND ANIMALS | HESKA CORPORATION (US) | 2000-05-16 | — | — | US | disclosed |