Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26222748 | 0.85 | EGFR (0.59) | ALDH1A1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL5272815 | 0.84 | EGFR (0.59) | ALDH1A1CYP1A2CYP3A4CYP2C9MAPK1 | |
| N-Sec-Butylcinnamamide SCHEMBL24740108 | 0.84 | ALDH1A1 (0.69) | ALDH1A1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL31661815 | 0.84 | EGFR (0.61) | ALDH1A1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL10983632 | 0.81 | ALDH1A1 (0.69) | ALDH1A1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL11125448 | 0.80 | ALDH1A1 (0.84) | ALDH1A1GAASMN1; SMN2HTTMAPT | |
| SCHEMBL11125445 | 0.80 | ALDH1A1 (0.84) | ALDH1A1GAASMN1; SMN2HTTMAPT | |
| SCHEMBL6465249 | 0.80 | ADH1B (0.50) | ALDH1A1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL21336468 | 0.80 | ALDH1A1 (0.68) | ALDH1A1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL11098283 | 0.80 | ALDH1A1 (0.60) | ALDH1A1MAPK1GAALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293535-A1 | ERBB/BTK INHIBITORS | DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) | 2023-09-21 | — | — | US | disclosed |
| EP-3205650-A1 | EGFR INHIBITOR, AND PREPARATION AND APPLICATION THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2017-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230293535-A1 | ERBB/BTK INHIBITORS | ERBB2, BTK, ERBB3 | ALDH1A1 4856/4885CYP1A2 4302/4885CYP3A4 3778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.