Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.33 |
| ▸ | CTSA | P10619 | 2/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 2/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13733347 | 0.90 | PTPN1 (0.35) | PTGDR2DHODHPTPN1IKBKBPPARD | |
| SCHEMBL13734189 | 0.89 | PTGDR2 (0.36) | PTGDR2DHODHIKBKBSCN9A | |
| SCHEMBL19210490 | 0.88 | PTGDR2 (0.38) | PTGDR2DHODHPTPN1CTSAIKBKB | |
| SCHEMBL13732560 | 0.87 | PTGDR2 (0.35) | PTGDR2DHODHPTPN1CTSAIKBKB | |
| SCHEMBL13826889 | 0.86 | PTGDR2 (0.34) | PTGDR2DHODHCTSAIKBKBSCN9A | |
| SCHEMBL13732961 | 0.85 | PTGDR2 (0.34) | PTGDR2DHODHPTPN1CTSAIKBKB | |
| SCHEMBL19210465 | 0.85 | PTGDR2 (0.33) | PTGDR2DHODHPTPN1IKBKB | |
| SCHEMBL13732333 | 0.84 | HSD11B1 (0.34) | IKBKBPPARDSCN9A | |
| SCHEMBL13732883 | 0.84 | PTGDR2 (0.33) | PTGDR2DHODHPTPN1CTSAIKBKB | |
| SCHEMBL13732675 | 0.84 | SCN9A (0.36) | PTGDR2DHODHPTPN1CTSAIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699557-B1 | 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2017-08-16 | — | — | EP | claimed |