Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19210456 | 0.92 | RXRA (0.35) | PTGDR2DHODHFFAR4CTSAFFAR1 | |
| SCHEMBL13734658 | 0.90 | PTPN1 (0.34) | PTGDR2DHODHFFAR4PTPN1IKBKB | |
| SCHEMBL13734189 | 0.90 | PTGDR2 (0.36) | PTGDR2DHODHIKBKB | |
| SCHEMBL19210414 | 0.89 | PTGDR2 (0.33) | PTGDR2DHODHFFAR4CTSAPTPN1 | |
| SCHEMBL19210465 | 0.89 | PTGDR2 (0.33) | PTGDR2DHODHPTPN1IKBKB | |
| SCHEMBL19210399 | 0.88 | PTGDR2 (0.37) | PTGDR2DHODHCTSAPTPN1IKBKB | |
| SCHEMBL13732560 | 0.87 | PTGDR2 (0.35) | PTGDR2DHODHCTSAPTPN1IKBKB | |
| SCHEMBL19210401 | 0.87 | FFAR4 (0.35) | PTGDR2DHODHFFAR4PTPN1FFAR1 | |
| SCHEMBL13826889 | 0.87 | PTGDR2 (0.34) | PTGDR2DHODHCTSAIKBKB | |
| SCHEMBL13732961 | 0.86 | PTGDR2 (0.34) | PTGDR2DHODHCTSAPTPN1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699557-B1 | 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2017-08-16 | — | — | EP | claimed |